Rationale: There are limited real-world data regarding the proportion of patients with severe asthma (SA) who achieve clinical remission with biologic treatment. Methods: CHRONICLE is an observational study of subspecialist-treated adults with SA. Sites report exacerbations and biologic use from 12 months prior to enrollment forward. Monthly Asthma Control Test (ACT) scores and 6-monthly specialist assessments of asthma control are collected. Clinical remission was... Read More

The modernization of healthcare is critical to all clinicians, especially those who treat patients with chronic pain. Preliminary data suggests that mHealth technology can improve treatment plan adherence, medication protocol compliance and lead to improved patient outcomes. The mHealth platform described bridges a treatment gap that occurs between visits and has been demonstrated to improve clinically important outcomes. Improving physician-patient communication in... Read More

Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness, cataplexy, and other REM-dissociative features. Assessment of treatment response requires evaluating multiple domains that include narcolepsy symptoms, comorbid psychiatric conditions (e.g., anxiety, depression, ADHD), quality of life, and medication side effects. Existing scales may be insufficient to capture the dynamic and personalized changes that occur visit by visit... Read More